• Methylcobalamin is the active form of vitamin B12 for maximum benefit • Superior bioavailability to the more common form, cyanocobalamin, which does not convert to enough methylcobalamin to correct some forms of anemia, neurological defects, and aging1 • Lowers homocysteine levels for protective cardiovascular benefits • Sublingual tablets allow for fast acting delivery system directly into blood stream
Vitamin B12 is the cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as for the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine.2 A B12 deficiency causes impairments in both of these pathways, disrupting neurological function, including poor formation of myelin nerve sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.3,4 Methylcobalamin, the principal circulating form of B12 and the one transported into peripheral tissues, has been shown to not only reduce homocysteine, but also to reduce inflammatory factors and the volume of carotid artery plaques among stroke patients, as well as pain, and neuropathy among diabetics.5-8 Because of its relationship to myelin production and neurological function, high dose B12 has been used in a variety of neurodegenerative diseases, including Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis.9–12
Some individuals, especially those with malabsorption or low dietary intake, are at higher risks for a B12 deficiency. Individuals with impaired absorption of B12 rely on passive absorption, which is typically 1% of the ingested amount. Thus, high doses may be required for those with greater B12 needs, such as elderly individuals and those with neurodegenerative disorders.13,14
Quantity
60 Sublingual Tablets
Dose
Recommended Adult Dose: 1 tablet per day or as directed by a health care practitioner. Dissolve under the tongue. Consult a health care practitioner for use beyond 4 months.
<a name="p1"> </a><h3>Indications</h3>
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• Methylcobalamin is the active form of vitamin B12 for maximum benefit • Superior bioavailability to the more common form, cyanocobalamin, which does not convert to enough methylcobalamin to correct some forms of anemia, neurological defects, and aging1 • Lowers homocysteine levels for protective cardiovascular benefits • Sublingual tablets allow for fast acting delivery system directly into blood stream
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Cake\View\View->_render() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/View/View.php, line 810
Cake\View\View->render() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/Controller.php, line 790
Cake\Controller\Controller->render() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/Controller.php, line 569
Cake\Controller\Controller->invokeAction() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/ControllerFactory.php, line 140
Cake\Controller\ControllerFactory->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/ControllerFactory.php, line 115
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Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 67
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Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php, line 68
Cake\Routing\Middleware\AssetMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
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Cake\Http\Server->run() /home/ndassist/nhpassist.com/webroot/index.php, line 40
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Dose
Recommended Adult Dose: 1 tablet per day or as directed by a health care practitioner. Dissolve under the tongue. Consult a health care practitioner for use beyond 4 months.
