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Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative.
Barberry Root, Barberry Root Extract, Goldenseal Root, Oregon Grape Root, Oregon Grape Root Extract
Combination of berberine extracts from natural plant sources
Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative
Includes goldenseal root extract, barberry root extract, barberry root bark, Oregon grape root extract, and Oregon grape root
Berberis Formula is a blend of barberry, goldenseal and Oregon grape extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.1,2 Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.3
Berberine also mediates the transport of ions and water across intestinal epithelial cells.3
It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3
Berberine can increase the expression of the Na+;H+ exchanger and aquaporin 2, which help enhance the absorption of sodium and water, respectively.3,4 Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.5 During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect.6
NPN 80034907
07519
1. Javadzadeh, SM, Ebrahimi, A. The traditional uses and pharmacological effects of different parts Berberis Vulgaris. Sci. Agri. 2013; 1(2): 61-66.
2. Siow, YL, Sarna, L, O, K. Redox regulation in health and disease - Therapeutic potential of berberine. Food Research International. 2011; 44: 2409-2417.
3. Chen, C, Yu, Z, Li, Y, Fichna, J, Storr, M. Effects of Berberine in the Gastrointestinal Tract - A Review of Actions and Therapeutic Implications. The American Journal of Chinese Medicine. 2014; 42(5): 1053-1070.
4. Zhang, Y, Wang, X, Sha, S, Liang, S, Zhao, L, Liu, L, Chai, N, Wang, H, Wu, K. Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model. Fitoterapia. 2012; 83: 1014-1022.
5. Gu, L, Li, N, Gong, J, Li, Q, Zhu, W, Li, J. Berberine Ameliorates Intestinal Epithelial Tight-Junction Damage and Down-regulates Myosin Light Chain Kinase Pathways in a Mouse Model of Endotoxinemia. The Journal of Infectious Diseases. 2011; 203: 1602-1612.
6. Chen, DP, Xiong, YJ, Lv, BC, Liu, FF, Wang, L, Tang, ZY, Lin, Y. Effects of berberine on rat jejunal motility. Journal of Pharmacy and Pharmacology. 2013; 65(5): 734-744.
90 caps
Recommended Adult Dose: Take 1 capsule 2 times daily with meals or as recommended by your healthcare practitioner. May take up to 1 week to produce beneficial effects.
Risk Information: Do not use if you are pregnant or breastfeeding. Do not exceed the recommended dose. Consult your healthcare practitioner prior to use if you have a kidney disorder, blood pressure problems, heart or respiratory condition. Avoid taking with alcohol, other medications or natural health products with sedative properties. Stop use and consult your healthcare practitioner if the following symptoms occur: nausea, vomiting, drop in blood pressure or difficulty breathing. Consult your healthcare practitioner if symptoms persist or worsen. High dosages of berberine can depress respiration, stimulate intestinal smooth muscle and reduce bronchial constriction.
Disclaimer: This content is subject to change. The information is intended to inform and educate; it does not replace the medical evaluation, advice, diagnosis or treatment by a healthcare professional. www.nhpassist.com © 2014 NDAssist Inc. and/or its affiliates. All rights reserved.
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Berberis Formula 90cIndications
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Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative. IngredientsBarberry Root, Barberry Root Extract, Goldenseal Root, Oregon Grape Root, Oregon Grape Root Extract Quantity
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DoseRecommended Adult Dose: Take 1 capsule 2 times daily with meals or as recommended by your healthcare practitioner. May take up to 1 week to produce beneficial effects. Potential side effects/SafetyRisk Information: Do not use if you are pregnant or breastfeeding. Do not exceed the recommended dose. Consult your healthcare practitioner prior to use if you have a kidney disorder, blood pressure problems, heart or respiratory condition. Avoid taking with alcohol, other medications or natural health products with sedative properties. Stop use and consult your healthcare practitioner if the following symptoms occur: nausea, vomiting, drop in blood pressure or difficulty breathing. Consult your healthcare practitioner if symptoms persist or worsen. High dosages of berberine can depress respiration, stimulate intestinal smooth muscle and reduce bronchial constriction. |
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